Built on 46 ICH/FDA guidelines with AI-powered analysis

Know exactly what FDA needs — before you submit

Upload preclinical study reports. Get instant compliance analysis against ICH/FDA requirements. See what's missing, what's ready, and what to do next.

The preclinical compliance problem

Biotech companies lose time and money discovering regulatory gaps too late. Manual processes create bottlenecks that delay FDA submissions.

40%

Protocol Amendments

of IND submissions require protocol amendments due to preclinical data gaps identified too late in the process.

200+ hrs

Manual FDA Cross-Referencing

spent manually cross-referencing study reports against ICH guidelines and FDA requirements for each submission.

6-12 mo

IND-Readiness Bottleneck

average delay when compliance gaps are discovered during IND preparation rather than during study planning.

Your regulatory team is cross-referencing study reports against ICH M3, S7A, S2, and a dozen other guidelines — manually, in spreadsheets, over weeks. One missed requirement doesn't just mean a revision. It means a clinical hold. A delayed trial. Months of lost time. And you won't know until FDA reviews your package.

Know what's missing before FDA does.

Upload your preclinical study reports. In minutes, Regfo extracts key data, maps it against ICH/FDA requirements, and gives you a compliance score with specific gaps and action items.

Start Free

How it works

From document upload to compliance report in four steps.

Upload Study Reports

Upload PDF or DOCX preclinical study reports — toxicology, safety pharmacology, PK/ADME, genotoxicity. Our AI processes each document automatically.

AI-Powered Data Extraction

AI reads each report, identifies study type, species, GLP status, key findings, NOAEL/LOAEL values, and structures the data for compliance analysis.

Automated Compliance Analysis

Your study package is evaluated against ICH M3(R2), S7A/B, S2, and other FDA requirements. Get a compliance score, identify gaps, and see prioritized actions.

Share with Your Team

Generate a shareable link to your compliance report. Regulatory affairs, project managers, and CROs can review the analysis without creating an account.

Your Regulatory Intelligence Dashboard

See compliance scores, gap analysis, risk assessment, and action items — all in one workspace. Every document processed, every requirement tracked.

Score

73

Nearly Ready

Documents

5

All processed

Gaps Found

3

1 critical

Actions

7

Prioritized

Study Coverage

Toxicology80%
Safety Pharmacology60%
Genotoxicity100%
PK/ADME50%

Critical Gaps

Missing repeat-dose toxicity in non-rodent species

Cardiovascular safety (hERG) not GLP-compliant

PK repeat-dose study needed

Compliance Score

Real-time 0-100 score based on ICH/FDA requirements coverage for your target development phase.

Gap Analysis

Automatically identifies missing studies, insufficient species coverage, and GLP compliance issues.

Risk Assessment

Severity-rated risks with regulatory references and specific mitigation recommendations.

Action Items

Prioritized list of studies to conduct and data to gather, with timeline estimates.

Why regulatory teams choose Regfo

Real regulatory citations

Not generic AI advice. Every finding references specific ICH guidelines and FDA requirements.

46 data points per study

Study type, species, GLP status, NOAEL, target organs — extracted automatically from PDF/DOCX.

Share with one click

Send compliance reports to your team or CRO. No account required for viewers.

Pricing

Choose the plan that fits your regulatory needs

Billed annually

Free

$0

1 workspace
Up to 5 documents
Basic compliance check
Community support

Pro

$4,990 /year

Unlimited workspaces
Unlimited documents
AI-powered extraction
Full compliance analysis
Share links
Priority support

Team

$14,990 /year

Everything in Pro
Up to 10 users
Team workspaces
Audit trail
Custom compliance rules
Dedicated support

Frequently Asked Questions

Common questions about Regfo and regulatory compliance analysis.

Start analyzing your preclinical package

Upload study reports, run compliance analysis against ICH/FDA requirements, and see exactly what your IND submission needs.

Free plan includes 1 workspace and 5 documents. No credit card required.